What is MT-2 (Melanotan 2 Acetate)?
Melanotan 2 Acetate, commonly referred to as MT-2, is a synthetic analogue of the naturally occurring peptide hormone alpha-melanocyte-stimulating hormone (α-MSH). It is primarily known for its ability to stimulate melanin production, which results in skin tanning. MT-2 is often used by individuals seeking a darker complexion without excessive sun exposure.
How Does MT-2 Work?
MT-2 works by binding to melanocortin receptors in the body, particularly the MC1R receptor, which stimulates the production of melanin in the skin. This results in:
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Increased pigmentation (tanning)
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Reduced risk of sunburn
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Enhanced photoprotection from UV damage
Besides its tanning effects, MT-2 can also interact with other melanocortin receptors (MC3R, MC4R), which may influence libido, appetite, and energy levels.
Common Uses of MT-2
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Cosmetic tanning
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Protection against UV radiation
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Potential sexual health applications (due to reported libido-enhancing effects)
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Research into appetite control and obesity
Benefits of Melanotan 2 Acetate
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Achieves a natural-looking tan without prolonged sun exposure
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May help prevent UV-related skin damage
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Can reduce the risk of sunburn in individuals with fair skin
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May offer potential sexual health benefits (e.g., increased libido and erectile function)
Possible Side Effects
Like any research peptide, MT-2 may cause temporary or mild side effects, including:
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Nausea
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Flushing
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Appetite suppression
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Darkening of moles or freckles
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Fatigue or yawning
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Increased libido or spontaneous erections
Most side effects are dose-dependent and may lessen with continued use.
Dosage and Administration
MT-2 is typically administered via subcutaneous injection. Users usually start with a loading phase followed by a maintenance dose:
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Loading phase: 250–500 mcg daily until desired pigmentation is achieved
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Maintenance phase: 250 mcg every 2–3 days
Dosage should always be tailored individually and used with proper medical oversight.
Legal Status and Caution
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MT-2 is sold for research purposes only in many countries.
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It is not approved by the FDA for human use.
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Users should be cautious of unregulated sources and consult a healthcare professional before considering use.




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