CJC-1295 without DAC (Drug Affinity Complex) is a synthetic peptide that stimulates the natural release of growth hormone (GH) by mimicking growth hormone-releasing hormone (GHRH). Unlike its counterpart with DAC, this version has a shorter half-life, offering pulsatile GH release, which is believed to more closely replicate the body’s natural secretion patterns.
How It Works
CJC-1295 without DAC binds to the GHRH receptors in the pituitary gland, promoting growth hormone release in a more controlled, natural rhythm. It is often used in conjunction with another peptide like Ipamorelin, which targets a different receptor, to amplify GH production without increasing cortisol or prolactin levels.
Benefits of CJC-1295 Without DAC
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✅ Increased lean muscle mass
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✅ Reduced body fat
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✅ Improved sleep quality
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✅ Enhanced recovery from workouts
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✅ Support for anti-aging and cellular repair
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✅ Boosted immune function and metabolism
Key Differences (Without DAC vs. With DAC)
| Feature | CJC-1295 Without DAC | CJC-1295 With DAC |
|---|---|---|
| Half-life | ~30 minutes | ~8 days |
| Dosing Frequency | Multiple times per day | 1–2 times per week |
| GH Release Pattern | Pulsatile (natural rhythm) | Continuous (non-pulsatile) |
| Risk of desensitization | Lower | Higher |
Dosing Protocol
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Typical Dose: 100–200 mcg per injection
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Frequency: 1–3 times daily (usually morning, post-workout, and before bed)
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Administration: Subcutaneous injection
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Cycle Duration: 8–12 weeks, followed by a break
Note: Always consult with a healthcare provider before starting any peptide therapy.
Possible Side Effects
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Mild irritation at injection site
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Temporary flushing or tingling
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Headaches
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Water retention (rare)
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Lethargy in some users
Conclusion
CJC-1295 without DAC is a preferred choice for those who want a more natural, safer stimulation of growth hormone release. Its short half-life and pulsatile GH release make it popular among athletes, bodybuilders, and individuals interested in longevity or improved recovery.




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